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What is Synvisc-One?

Synvisc-One is a way to treat your osteoarthritis (OA) knee pain right at the source. Made from a natural substance that lubricates and cushions your joint, it can provide up to six months of knee pain relief with just one injection.

How does Synvisc-One work?

In knees with osteoarthritis, the joint fluid (called synovial fluid) can break down and not provide the cushioning your knee needs. Synvisc-One supplements your knee fluid to relieve the pain and improve the knee joint’s natural shock absorbing abilities.

Image of knee with Osteoarthritis before treatment with SYNVISC
A. Cartilage wears away
B. Bone spurs may develop
C. Joint fluid breaks down
Image of knee with Osteoarthritis after treatment with SYNVISC
D. Synvisc-One

 

How is Synvisc-One given?

Synvisc-One is a single injection. It’s a simple, in-office procedure that only takes a few minutes. After the injection, you can resume normal day-to-day activities but you should avoid any strenuous activities for about 48 hours.

What can I expect from Synvisc-One treatment?

Synvisc-One can provide up to six months of osteoarthritis knee pain relief. Everyone responds differently, but in a medical study patients experienced relief starting one month after the injection. Synvisc-One can be repeated safely, so keep track of your symptoms and talk with your doctor if your knee pain begins to return.

What are the side effects?

The side effects most commonly seen in a medical study were knee pain, stiffness and swelling or fluid buildup in or around the knee. Other side effects, such as rash, may also occur. Side effects were generally mild to moderate and did not last long. Synvisc-One does not have the serious side effects associated with many pain pills. 

How is Synvisc-One different from SYNVISC?

Synvisc-One is the same formulation as SYNVISC. The only difference is that Synvisc-One is provided with one injection compared to three injections required for SYNVISC. Both treatments can provide up to six months of pain relief.

Alain Elbaz, MD. – Orthopaedic Surgeon Meet Dr Alain Elbaz
Alain Elbaz, MD.
Orthopaedic Surgeon
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Indication

Synvisc-One® (hylan G-F 20) and SYNVISC® (hylan G-F 20) are indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen.

 

Important Safety Information

Before trying Synvisc-One or SYNVISC, tell your doctor if you are allergic to products from birds—such as feathers, eggs or poultry—or if your leg is swollen or infected. Synvisc-One and SYNVISC are only for injection into the knee, performed by a doctor or other qualified health care professional. Synvisc-One and SYNVISC have not been tested to show pain relief in joints other than the knee. Talk to your doctor before resuming strenuous weight-bearing activities after treatment. Synvisc-One and SYNVISC have not been tested in children, pregnant women or women who are nursing. You should tell your doctor if you think you are pregnant or if you are nursing a child. The side effects most commonly seen when Synvisc-One or SYNVISC is injected into the knee were pain, swelling and/or fluid buildup in or around the knee. Cases where the swelling is extensive or painful should be discussed with your doctor. Allergic reactions such as rash and hives have been reported rarely.

View the Complete Prescribing Information for Synvisc-One (PDF)
View the Complete Prescribing Information for SYNVISC (PDF)

 

© Alain Elbaz MD Orthopaedic Hip Knee & Shoulder Surgeon Cypress Houston Texas