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Treatment with Synvisc-One® (hylan G-F 20)

Here's what to expect during and after treatment with Synvisc-One. As always, consult with your doctor when you need to know more.

Before your visit

Synvisc-One is a local therapy that should not interact with other medications you are taking. Still, be sure to tell your doctor if you are taking any medications, including over-the-counter drugs.

During the procedure

To prepare your knee for the injection, your doctor may:

  1. Clean your knee with alcohol and iodine
  2. Apply a local anesthetic to your knee
  3. Withdraw excess fluid from your joint

The doctor will then inject your knee with Synvisc-One. The whole procedure should only take a few minutes, and you'll be able to go home immediately after the treatment.

When you get home

  • If you have any mild pain or swelling at the injection site, you may want to keep an ice pack on your knee for 15-20 minutes, or as recommended by your doctor.
  • Avoid putting a lot of strain on your knee - such as jogging, lifting or prolonged standing - for 48 hours after the injection, or as recommended by your doctor.

Possible side effects

The side effects most commonly seen in a medical study were generally mild to moderate and did not last long. They may include:

  • Knee pain
  • Stiffness
  • Swelling or fluid buildup in or around the knee

Other side effects, such as rash, may also occur. If you experience any side effects, be sure to discuss them with your doctor.

Alain Elbaz, MD. – Orthopaedic Surgeon Meet Dr Alain Elbaz
Alain Elbaz, MD.
Orthopaedic Surgeon
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Indication

Synvisc-One® (hylan G-F 20) and SYNVISC® (hylan G-F 20) are indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen.

 

Important Safety Information

Before trying Synvisc-One or SYNVISC, tell your doctor if you are allergic to products from birds—such as feathers, eggs or poultry—or if your leg is swollen or infected. Synvisc-One and SYNVISC are only for injection into the knee, performed by a doctor or other qualified health care professional. Synvisc-One and SYNVISC have not been tested to show pain relief in joints other than the knee. Talk to your doctor before resuming strenuous weight-bearing activities after treatment. Synvisc-One and SYNVISC have not been tested in children, pregnant women or women who are nursing. You should tell your doctor if you think you are pregnant or if you are nursing a child. The side effects most commonly seen when Synvisc-One or SYNVISC is injected into the knee were pain, swelling and/or fluid buildup in or around the knee. Cases where the swelling is extensive or painful should be discussed with your doctor. Allergic reactions such as rash and hives have been reported rarely.

View the Complete Prescribing Information for Synvisc-One (PDF)
View the Complete Prescribing Information for SYNVISC (PDF)

 

© Alain Elbaz MD Orthopaedic Hip Knee & Shoulder Surgeon Cypress Houston Texas