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Osteoarthritis

Arthritis Glossary

Acetaminophen
An over-the-counter drug that relieves pain and reduces fever; brand name Tylenol®.

Arthritis
A joint disease that can cause joint pain, swelling, stiffness and/or redness of the skin over the joint.

Cartilage
A type of connective tissue found in many parts of the skeleton; a type called "articular" cartilage is very slippery and covers the ends of bones in joints.

COX-2 inhibitor
A newer subclass of NSAID medication that directly targets COX-2, an enzyme responsible for inflammation and pain; available by prescription only; for example, celecoxib (Celebrex®).

NSAID
Nonsteroidal anti-inflammatory drug, a class of medication that reduces inflammation and pain; includes aspirin, ibuprofen (for example, Motrin® and Advil®) and naproxen (for example, Aleve®).

Osteoarthritis
A joint disease characterized by a breakdown of the joint’s cartilage and normal synovial fluid; symptoms include pain and stiffness.

Steroid
A class of drugs resembling normal body substances that can help control inflammation in body tissues.

Synovial fluid
The hyaluronan-containing fluid found in the joint that nourishes cartilage and lubricates and cushions the joint.

SYNVISC® (hylan G-F 20)
A treatment of osteoarthritis of the knee consisting of a thick, elastic fluid made from hylans. SYNVISC is similar to fluid found in a normal, healthy knee. It is injected into the knee to replace damaged synovial fluid, reduce pain and improve function.

Viscosupplement
A substance that mimics the synovial fluid found in healthy joints and is injected into knees with osteoarthritis to reduce pain and improve function as well.

Viscosupplementation
An injection that replaces diseased synovial (joint) fluid in osteoarthritic knees in order to reduce pain and improve function as well.

Brand References

  • Tylenol is a registered trademark of McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

  • Celebrex is a registered trademark of Pfizer, Inc.

  • Motrin is a registered trademark of McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

  • Advil is a registered trademark of Wyeth Consumer Healthcare

  • Aleve is a registered trademark of Bayer Consumer Care, LLC.
Alain Elbaz, MD. – Orthopaedic Surgeon Meet Dr Alain Elbaz
Alain Elbaz, MD.
Orthopaedic Surgeon
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Indication

Synvisc-One® (hylan G-F 20) and SYNVISC® (hylan G-F 20) are indicated for the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics, e.g., acetaminophen.

 

Important Safety Information

Before trying Synvisc-One or SYNVISC, tell your doctor if you are allergic to products from birds—such as feathers, eggs or poultry—or if your leg is swollen or infected. Synvisc-One and SYNVISC are only for injection into the knee, performed by a doctor or other qualified health care professional. Synvisc-One and SYNVISC have not been tested to show pain relief in joints other than the knee. Talk to your doctor before resuming strenuous weight-bearing activities after treatment. Synvisc-One and SYNVISC have not been tested in children, pregnant women or women who are nursing. You should tell your doctor if you think you are pregnant or if you are nursing a child. The side effects most commonly seen when Synvisc-One or SYNVISC is injected into the knee were pain, swelling and/or fluid buildup in or around the knee. Cases where the swelling is extensive or painful should be discussed with your doctor. Allergic reactions such as rash and hives have been reported rarely.

View the Complete Prescribing Information for Synvisc-One (PDF)
View the Complete Prescribing Information for SYNVISC (PDF)

 

© Alain Elbaz MD Orthopaedic Hip Knee & Shoulder Surgeon Cypress Houston Texas